High (>50%) risk of death from lung disease within 2 years if lung transplantation is not performed | Too early in the disease course |
Recent history of malignancy |
High (>80%) likelihood of surviving at least 90 days after lung transplantation | Poorly controlled, chronic infection with highly virulent or resistant |
microbes |
High (>80%) likelihood of 5-year post-transplant survival given adequate graft function | Active Mycobacterium tuberculosis infection |
Untreatable dysfunction in another organ class# |
| Acute medical instability |
Uncorrected atherosclerotic disease |
| Uncorrectable bleeding diathesis |
| Significant chest wall or spinal deformity that may cause severe restriction after transplantation |
| Body mass index >35.0 kg·m−2 |
| Current or a history of non-compliance to medical therapy |
Psychiatric or psychological conditions associated with inability to adhere to medical therapy |
| Substance abuse or dependence |
| Absence of an adequate or reliable social support system |
| Severely limited functional status with poor rehabilitation potential |