Blood tests | Normal FBC, BCP and inflammatory markers Positive ANA titre >1:640 Negative ANCA Negative antineuronal antibodies Negative acetylcholine receptor antibodies Negative voltage-gated calcium channel antibodies | Normal FBC, BCP and inflammatory markers | Normal FBC, BCP and inflammatory markers | Normal FBC, BCP and inflammatory markers Normal blood glucose, vitamin E and B12 Normal antiGQ1B antibody levels |
Lung function | Normal | Normal | Normal | Normal |
Radiology | Normal chest radiograph, cervical spine MRI and body CT scan | Normal chest radiograph and HRCT | Normal chest radiograph | Normal chest radiograph |
HARQ score# | | 45/70 | 36/70 | |
Other | DeMeester score 18.3+ CSF analysis: normal protein, glucose and cells and negative for oligoclonal bands | OGD: small hiatus hernia | BMI 38.2 kg·m−2 Normal FeNO Normal citric acid cough challenge: 2 coughs 37.5 mM, 5 coughs 56.25 mM | Negative methacholine challenge test Normal citric acid cough challenge: 2 coughs 407 mM |
Autonomic test: HRV¶ | 9 beats·min−1 | 4 beats·min−1 | 9.75 beats·min−1 | |