Airways and their mucosa
|
Luminal defence mechanisms |
Anatomical barrier |
Cough |
Mucociliary clearance |
Secretory IgA |
Lysozymes, lactoferrins |
Defensins |
Epithelial cells |
Epithelial barrier |
Mucin release |
Antimicrobial peptides |
Bacterial receptors |
Chemotactic factors |
Growth factors; cytokines |
Blood derived cells of the mucosa |
Dendritic cells |
Lymphocytes (T-cells; γδ; NK cells) |
B lymphocytes |
Eosinophils; mast cells; basophils |
Alveolar spaces
|
Pneumocyte types I and II |
Alveolar macrophages |
Lymphocytes |
Neutrophils |
IgG and opsonins |
Surfactant |