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Exhaled nitric oxide in childhood asthma: methodological issues and clinical applications

Erasmusmc – Sophia Children's Hospital, University Medical Centre, Dept of Paediatrics, Rotterdam, The Netherlands

CORRESPONDENCE: Mariëlle Pijnenburg, Erasmusmc – Sophia Children's Hospital, University Medical Centre, Dept of Paediatrics, Rotterdam, The Netherlands

The work described herein was presented as an oral, invited presentation at the European Respiratory Society (ERS) Congress 2006 and was awarded the European Respiratory Society Annual Award for Paediatric Respiratory Research in Europe; the work consists of two parts. The first part is on methodological issues of measuring exhaled nitric oxide fraction (F_e,NO) in children. The second part includes four studies on clinical applications of F_e,NO measurements in asthmatic children.